| Date | Location | Result | |
| 03/04/10 | Conway, S.C. (Kimbel Arena) | Winthrop 61, Radford 46 | Box score |
| 03/02/10 | Radford, Va. -- Dedmon Center | Radford 64, Charleston Southern 61 | Box score |
| 02/27/10 | Radford, Va. -- Dedmon Center | Radford 54, Winthrop 52 | Box score |
| 02/25/10 | Radford, Va. -- Dedmon Center | Radford 75, Presbyterian 58 | Box score |
| 02/20/10 | Radford, Va. -- Dedmon Center | Radford 76, UNC Wilmington 68 | Box score |
| 02/16/10 | Lynchburg, Va. - Vines Center | Radford 74, Liberty 69 | Box score |
| 02/13/10 | Radford, Va. -- Dedmon Center | Coastal Carolina 52, Radford 51 | Box score |
| 02/11/10 | Radford, Va. -- Dedmon Center | Radford 61, Charleston Southern 58 | Box score |
| 02/07/10 | Radford, Va. -- Dedmon Center | Radford 77, High Point 63 | Box score |
| 02/02/10 | Lexington, Va. (Cameron Hall) | Radford 111, VMI 84 | Box score |
| 01/31/10 | Asheville, N.C./Justice Center | UNC Asheville 92, Radford 84 | Box score |
| 01/28/10 | Boiling Springs, NC / Paul Porter Arena | Radford 80, Gardner-Webb 73 | Box score |
| 01/25/10 | Harrisonburg, Va. -- Convocation Center | James Madison 67, Radford 63 | Box score |
| 01/23/10 | Radford, Va. -- Dedmon Center | Liberty 60, Radford 55 | Box score |
| 01/21/10 | Radford, Va. -- Dedmon Center | Radford 109, VMI 91 | Box score |
| 01/16/10 | CSU Field House, Charleston, S.C. | Charleston Southern 70, Radford 55 | Box score |
| 01/14/10 | Kimbel Arena, Conway, S.C. | Radford 62, Coastal Carolina 52 | Box score |
| 01/09/10 | Millis Center (High Point, N.C.) | High Point 83, Radford 77 | Box score |
| 01/04/10 | Radford, Va. -- Dedmon Center | Radford 75, Gardner-Webb 45 | Box score |
| 01/02/10 | Radford, Va. -- Dedmon Center | Radford 82, UNC Asheville 74 | Box score |
| 12/30/09 | Radford, Va. -- Dedmon Center | Radford 80, George Mason 53 | Box score |
| 12/27/09 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 79, Radford 53 | Box score |
| 12/22/09 | Radford, Va. -- Dedmon Center | William & Mary 70, Radford 68 | Box score |
| 12/13/09 | Radford, Va. (Dedmon Center) | Radford 99, Roanoke College 67 | Box score |
| 12/09/09 | Lawrence, Kan. (Allen Fieldhouse) | Kansas 99, Radford 64 | Box score |
| 12/05/09 | Clinton, S.C. | Radford 61, Presbyterian College 57 | Box score |
| 12/03/09 | Winthrop Coliseum--Rock Hill, SC | Radford 61, Winthrop 59 | Box score |
| 11/29/09 | Pittsburgh, Pa. / Palumbo Ctr. | Duquesne 71, Radford 63 | Box score |
| 11/21/09 | Durham, N.C. - Cameron Indoor Stadium | Duke 104, Radford 67 | Box score |
| 11/17/09 | Radford, Va. -- Dedmon Center | Radford 94, Lynchburg 70 | Box score |
| 11/13/09 | RADFORD, Va. -- Dedmon Center | Radford 76, NAVY 65 | Box score |